|JGG 1984, 11(6): 0-504 DOI: 500 ISSN: 1673-8527 CN: 11-5450/R|
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An Aberration of a Case with Three Translocations Involving Six Chromosomes
Zhang Zewei1, Zhou Yun1, Ming Deyi2, Zhang Wenqin2
1.Department of Biology,Liaoning University,Shenyang; 2.Institute of Planned Par enthood Research,Shenyang
In this paper we report a case of a chromosome structural aberration with three reciprocal translocations involving six chromosomes.The patient is a 10-month ma le infant.His major clinical feature is ocular hypertelorism,flat nasal bridge,l ow-set ears,severe mental retardation and narrow anus hole.The chromosome analys is of his peripheral blood lymphocyte using G-banding techniques shows the karyo type of 46,XY,t(2;3),t(6;15),t(7;14).It involves chromosomes Nos.2,3,6,15,7,14. As far as we know such chromosome structural aberration has not been reporte d in China and in the literature on chromosome aberrations.Three possible origin s of the chromosome structural aberration are considered,and the genetic effects of balanced translocation are discussed.
|Received 1900-01-01 Revised 1900-01-01 Online 1984-11-10|
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