The Polycomb Complex PRC1: Composition and Function in Plants

Anne Molitor^#,
Wen-Hui Shen^,

Institut de Biologie Moléculaire des Plantes du CNRS, Université de Strasbourg, 12 rue du Général Zimmer, 67084 Strasbourg, France

More Information

Corresponding author: E-mail address: wen-hui.shen@ibmp-cnrs.unistra.fr (Wen-Hui Shen)

Present address: Institut J.-P. Bourgin, UMR1318 INRA-AgroParisTech, INRA, route de Saint Cyr, 78026 Versailles, France.

摘要

- /
- /
- /
- /
Abstract: Polycomb group (PcG) proteins are crucial epigenetic regulators conferring transcriptional memory to cell lineages. They assemble into multi-protein complexes, e.g., Polycomb Repressive Complex 1 and 2 (PRC1, PRC2), which are thought to act in a sequential manner to stably maintain gene repression. PRC2 induces histone H3 lysine 27 (H3K27) trimethylation (H3K27me3), which is subsequently read by PRC1 that further catalyzes H2A monoubiquitination (H2Aub1), creating a transcriptional silent chromatin conformation. PRC2 components are conserved in plants and have been extensively characterized in Arabidopsis. In contrast, PRC1 composition and function are more diverged between animals and plants. Only more recently, PRC1 existence in plants has been documented. Here we review the aspects of plant specific and conserved PRC1 and highlight critical roles of PRC1 components in seed embryonic trait determinacy, shoot stem cell fate determinacy, and flower development in Arabidopsis.
- Epigenetics /
- Chromatin /
- Histone modifications /
- Polycomb /
- PRC1
Present address: Institut J.-P. Bourgin, UMR1318 INRA-AgroParisTech, INRA, route de Saint Cyr, 78026 Versailles, France.
注释:

HTML全文

参考文献(83)

[1]	Aichinger, E., Villar, C.B., Farrona, S. et al. PLoS Genet., 5 (2009),p. e1000605
[2]	Aubert, D., Chen, L., Moon, Y.H. et al. Plant Cell, 13 (2001),pp. 1865-1875
[3]	Bannister, A.J., Kouzarides, T. Regulation of chromatin by histone modifications Cell Res., 21 (2011),pp. 381-395
[4]	Bardos, J.I., Saurin, A.J., Tissot, C. et al. HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties J. Biol. Chem., 275 (2000),pp. 28785-28792
[5]	Barrero, J.M., Gonzalez-Bayon, R., Del Pozo, J.C. et al. Plant Cell, 19 (2007),pp. 2822-2838
[6]	Barton, M.K., Poethig, R.S. Development, 119 (1993),pp. 823-831
[7]	Beh, L.Y., Colwell, L.J., Francis, N.J. A core subunit of Polycomb repressive complex 1 is broadly conserved in function but not primary sequence Proc. Natl. Acad. Sci. USA, 109 (2012),pp. 1063-1071
[8]	Bouyer, D., Roudier, F., Heese, M. et al. Polycomb repressive complex 2 controls the embryo-to-seedling phase transition PLoS Genet., 7 (2011),p. e1002014
[9]	Bowman, J.L., Eshed, Y. Formation and maintenance of the shoot apical meristem Trends Plant Sci., 5 (2000),pp. 110-115
[10]	Bracken, A.P., Dietrich, N., Pasini, D. et al. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions Genes Dev., 20 (2006),pp. 1123-1136
[11]	Bratzel, F., Lopez-Torrejon, G., Koch, M. et al. Curr. Biol., 20 (2010),pp. 1853-1859
[12]	Brunk, B.P., Martin, E.C., Adler, P.N. Nature, 26 (1991),pp. 351-353
[13]	Buchwald, G., van der Stoop, P., Weichenrieder, O. et al. Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b EMBO J., 25 (2006),pp. 2465-2474
[14]	Calonje, M., Sanchez, R., Chen, L. et al. Plant Cell, 20 (2008),pp. 277-291
[15]	Chen, D., Molitor, A., Liu, C. et al. Cell Res., 20 (2010),pp. 1332-1344
[16]	Chen, L., Cheng, J.C., Castle, L. et al. Plant Cell, 11 (1997),pp. 2011-2024
[17]	Chen, L.J., Diao, Z.Y., Specht, C. et al. Molecular evolution of VEF-domain-containing PcG genes in plants Mol. Plant, 2 (2009),pp. 738-754
[18]	Cui, H., Benfey, P.N. Plant J., 58 (2009),pp. 1016-1027
[19]	de Napoles, M., Mermoud, J.E., Wakao, R. et al. Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation Dev. Cell, 7 (2004),pp. 663-676
[20]	Del Olmo, I., Lopez-Gonzalez, L., Martin-Trillo, M.M. et al. Plant J., 61 (2010),pp. 623-636
[21]	Dura, J., Ingham, P. Development, 103 (1988),pp. 733-741
[22]	Dura, J.M., Randsholt, N.B., Deatrick, J. et al. Cell, 51 (1987),pp. 829-839
[23]	Eissenberg, J.C. Structural biology of the chromodomain: form and function Gene, 496 (2012),pp. 69-78
[24]	Exner, V., Aichinger, E., Shu, H. et al. PLoS ONE, 4 (2009),p. e5335
[25]	Fischle, W., Wang, Y., Jacobs, S.A. et al. Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains Genes Dev., 17 (2003),pp. 1870-1881
[26]	Fritsch, C., Beuchle, D., Müller, J. Mech. Dev., 8 (2003),pp. 949-954
[27]	Gao, Z., Zhang, J., Bonasio, R. et al. PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes Mol. Cell, 45 (2012),pp. 344-356
[28]	Gaudin, V., Libault, M., Pouteau, S. et al. Development, 128 (2001),pp. 4847-4858
[29]	Germann, S., Juul-Jensen, T., Letarnec, B. et al. Plant J., 48 (2006),pp. 153-163
[30]	Goodrich, J., Puangsomlee, P., Martin, M. et al. Nature, 386 (1997),pp. 44-51
[31]	Grossniklaus, U., Vielle-Calzada, J.P., Hoeppner, M.A. et al. Science, 280 (1998),pp. 446-450
[32]	Gunster, M.J., Satijn, D., Hamer, K.M. et al. Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic Mol. Cell. Biol., 17 (1997),pp. 2326-2335
[33]	He, C., Chen, X., Huang, H. et al. PloS Genet., 8 (2012),p. e1002911
[34]	He, Y. Chromatin regulation of flowering Trends Plant Sci., 17 (2012),pp. 556-562
[35]	Holec, S., Berger, F. Polycomb group complexes mediate developmental transitions in plants Plant Physiol., 158 (2012),pp. 35-43
[36]	Jürgens, G. Nature, 316 (1985),pp. 153-155
[37]	Karakuzu, O., Wang, D.P., Cameron, S. Development, 136 (2009),pp. 943-953
[38]	Katz, A., Oliva, M., Mosquna, A. et al. FIE and CURLY LEAF polycomb proteins interact in the regulation of homeobox gene expression during sporophyte development Plant J., 37 (2004),pp. 707-719
[39]	Kim, S.Y., Lee, J., Eshed-Williams, L. et al. PLoS Genet., 8 (2012),p. e1002512
[40]	Ku, M., Koche, R.P., Rheinbay, E. et al. Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains PLoS Genet., 4 (2008),p. e1000242
[41]	Lafos, M., Kroll, P., Hohenstatt, M.L. et al. PLoS Genet., 7 (2011),p. e1002040
[42]	Latrasse, D., Germann, S., Houba-Herin, N. et al. Control of flowering and cell fate by LIF2, an RNA binding partner of the polycomb complex component LHP1 PLoS ONE, 6 (2011),p. e16592
[43]	Lee, T.I., Jenner, R.G., Boyer, L.A. et al. Control of developmental regulators by Polycomb in human embryonic stem cells Cell, 125 (2006),pp. 301-313
[44]	Levine, S.S., Weiss, A., Erdjument-Bromage, H. et al. The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans Mol. Cell. Biol., 22 (2002),pp. 6070-6078
[45]	Levy, Y.Y., Mesnage, S., Mylne, J.S. et al. Science, 297 (2002),pp. 243-246
[46]	Lewis, E.B. Nature, 276 (1978),pp. 565-570
[47]	Li, H., Luan, S. The cyclophilin AtCYP71 interacts with CAF-1 and LHP1 and functions in multiple chromatin remodeling processes Mol. Plant, 4 (2011),pp. 748-758
[48]	Li, W., Wang, Z., Li, J. et al. PLoS ONE, 6 (2011),p. e21364
[49]	Li, Z., Cao, R., Wang, M. et al. Structure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complex J. Biol. Chem., 281 (2006),pp. 20643-20649
[50]	Liu, C., Lu, F., Cui, X. et al. Histone methylation in higher plants Annu. Rev. Plant Biol., 61 (2010),pp. 395-420
[51]	Liu, C., Xi, W., Shen, L. et al. Regulation of floral patterning by flowering time genes Dev. Cell, 16 (2009),p. 1
[52]	Long, J.A., Moan, E.I., Medford, J.I. et al. Nature, 379 (1996),pp. 66-69
[53]	Lopez-Vernaza, M., Yang, S., Müller, R. et al. PLoS ONE, 7 (2012),p. e30715
[54]	Lu, F., Cui, X., Zhang, S. et al. Nat. Genet., 43 (2011),pp. 715-719
[55]	Luo, C., Sidote, D.J., Zhang, Y. et al. Plant J., 73 (2012),pp. 77-90
[56]	Margueron, R., Reinberg, D. The Polycomb complex PRC2 and its mark in life Nature, 469 (2011),pp. 343-349
[57]	Moon, Y.H., Chen, L., Pan, R.L. et al. Plant Cell, 15 (2003),pp. 681-693
[58]	Morey, L., Helin, K. Polycomb group protein-mediated repression of transcription Trends Biochem. Sci., 35 (2010),pp. 323-332
[59]	Mosquna, A., Katz, A., Decker, E.L. et al. Regulation of stem cell maintenance by the Polycomb protein FIE has been conserved during land plant evolution Development, 136 (2009),pp. 2433-2444
[60]	Mylne, J.S., Barrett, L., Tessadori, F. et al. Proc. Natl. Acad. Sci. USA, 103 (2006),pp. 5012-5017
[61]	Negre, N., Hennetin, J., Sun, L.V. et al. PLoS Biol., 4 (2006),p. e170
[62]	Ogawa, H., Ishiguro, K., Gaubatz, S. et al. A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells Science, 296 (2002),pp. 1132-1136
[63]	Roudier, F., Ahmed, I., Berard, C. et al. EMBO J., 30 (2011),pp. 1928-1938
[64]	Sanchez, C., Sanchez, I., Demmers, J.A. et al. Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor Mol. Cell. Proteomics, 6 (2007),pp. 820-834
[65]	Sanchez-Pulido, L., Devos, D., Sung, Z.R. et al. RAWUL: a new ubiquitin-like domain in PRC1 ring finger proteins that unveils putative plant and worm PRC1 orthologs BMC Genomics, 9 (2008),p. 308
[66]	Satijn, D., Gunster, M.J., van der Vlag, J. et al. RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor Mol. Cell. Biol., 17 (1997),pp. 4105-4113
[67]	Schoorlemmer, J., Marcos-Gutierrez, C., Were, F. et al. Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain EMBO J., 16 (1997),pp. 5930-5942
[68]	Schubert, D., Primavesi, L., Bishopp, A. et al. Silencing by plant Polycomb-group genes requires dispersed trimethylation of histone H3 at lysine 27 EMBO J., 25 (2006),pp. 4638-4649
[69]	Schuettengruber, B., Cavalli, G. Recruitment of polycomb group complexes and their role in the dynamic regulation of cell fate choice Development, 136 (2009),pp. 3531-3542
[70]	Schwartz, Y.B., Kahn, T.G., Nix, D.A. et al. Nat. Genet., 38 (2006),pp. 700-705
[71]	Schwartz, Y.B., Pirrotta, V. Polycomb silencing mechanisms and the management of genomic programmes Nat. Rev. Genet., 8 (2007),pp. 9-22
[72]	Shaver, S., Casas-Mollano, J.A., Cerny, R.L. et al. Origin of the Polycomb repressive complex 2 and gene silencing by an E(z) homolog in the unicellular alga Chlamydomonas Epigenetics, 5 (2010),pp. 301-312
[73]	Sung, S., He, Y., Eshoo, T.W. et al. Nat. Genet., 38 (2006),pp. 706-710
[74]	Tolhuis, B., de Wit, E., Muijrers, I. et al. Nat. Genet., 38 (2006),pp. 694-699
[75]	Turck, F., Roudier, F., Farrona, S. et al. PLoS Genet., 3 (2007),p. e86
[76]	Vidal, M. Role of polycomb proteins Ring1A and Ring1B in the epigenetic regulation of gene expression Int. J. Dev. Biol., 53 (2009),pp. 355-370
[77]	Wang, H., Wang, L., Erdjument-Bromage, H. et al. Role of histone H2A ubiquitination in Polycomb silencing Nature, 431 (2004),pp. 873-878
[78]	Wang, L., Brown, J.L., Cao, R. et al. Hierarchical recruitment of polycomb group silencing complexes Mol. Cell, 14 (2004),pp. 637-646
[79]	Whitcomb, S.J., Basu, A., Allis, C.D. et al. Polycomb Group proteins: an evolutionary perspective Trends Genet., 23 (2007),pp. 494-502
[80]	Xu, L., Shen, W.H. Curr. Biol., 18 (2008),pp. 1966-1971
[81]	Zhang, K., Sridhar, V.V., Zhu, J. et al. PLoS ONE, 2 (2007),p. e1210
[82]	Zhang, X., Clarenz, O., Cokus, S. et al. PLoS Biol., 5 (2007),p. e129
[83]	Zhang, X., Germann, S., Blus, B.J. et al. Nat. Struct. Mol. Biol., 14 (2007),pp. 869-871