Efficient Gene Targeting in Zebrafish Mediated by a Zebrafish-Codon-Optimized Cas9 and Evaluation of Off-Targeting Effect

Da Liu^{a, b, #},
Zhanxiang Wang^{a, #},
An Xiao^{a, #},
Yutian Zhang^a,
Wenyuan Li^a,
Yao Zu^{a, c},
Shaohua Yao^c,
Shuo Lin^{b, c},
Bo Zhang^{a
, ,}

a.
Key Laboratory of Cell Proliferation and Differentiation of the Ministry of Education, College of Life Sciences, Peking University, Beijing 100871, China
b.
Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China
c.
Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, CA 90095, USA

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Corresponding author: E-mail address: bzhang@pku.edu.cn (Bo Zhang)

These authors contributed equally to this work.

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These authors contributed equally to this work.

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参考文献(14)

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