Efficient Derivation of Human Induced Pluripotent Stem Cells with a c-Myc-Free Non-Integrating Episomal Vector

Juan Wang^{a, b, #},
Qi Gu^{b, c, #},
Jie Hao^{b, #},
Donghui Bai^b,
Liu Wang^b,
Zhonghua Liu^{a
, ,},
Qi Zhou^{b
, ,}

a.
College of Life Science, Northeast Agricultural University, Harbin 150030, China
b.
State Key Laboratory of Stem Cells and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China
c.
ARC Centre of Excellence for Electromaterials Science, Intelligent Polymer Research Institute, AIIM Facility, Innovation Campus, University of Wollongong, Squires Way, Fairy Meadow, New South Wales 2519, Australia

More Information

Corresponding author: E-mail address: liu086@126.com (Zhonghua Liu); E-mail address: zhouqi@ioz.ac.cn (Qi Zhou)

These authors contributed equally to this work.

摘要

These authors contributed equally to this work.

注释:

HTML全文

参考文献(20)

[1]	Caxaria, S., Arthold, S., Nathwani, A.C. et al. Generation of integration-free patient specific iPS cells using episomal plasmids under feeder free conditions Methods Mol. Biol., 1353 (2016),pp. 355-366
[2]	Hockemeyer, D., Soldner, F., Cook, E.G. et al. A drug-inducible system for direct reprogramming of human somatic cells to pluripotency Cell Stem Cell, 3 (2008),pp. 346-353
[3]	Hou, P., Li, Y., Zhang, X. et al. Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds Science, 341 (2013),pp. 651-654
[4]	Hu, B.Y., Weick, J.P., Yu, J. et al. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency Proc. Natl. Acad. Sci. USA, 107 (2010),pp. 4335-4340
[5]	Kim, D., Kim, C.H., Moon, J.I. et al. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins Cell Stem Cell, 4 (2009),pp. 472-476
[6]	Kriks, S., Shim, J.W., Piao, J. et al. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease Nature, 480 (2011),pp. 547-551
[7]	Kuzyk, A., Mai, S. c-MYC-induced genomic instability Cold Spring Harb. Perspect. Med., 4 (2014),p. a014373
[8]	Lee, A.S., Tang, C., Rao, M.S. et al. Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies Nat. Med., 19 (2013),pp. 998-1004
[9]	Miyoshi, N., Ishii, H., Nagano, H. et al. Reprogramming of mouse and human cells to pluripotency using mature microRNAs Cell Stem Cell, 8 (2011),pp. 633-638
[10]	Okita, K., Matsumura, Y., Sato, Y. et al. A more efficient method to generate integration-free human iPS cells Nat. Methods, 8 (2011),pp. 409-412
[11]	Piao, Y., Hung, S.S., Lim, S.Y. et al. Efficient generation of integration-free human induced pluripotent stem cells from keratinocytes by simple transfection of episomal vectors Stem Cells Transl. Med., 3 (2014),pp. 787-791
[12]	Schlaeger, T.M., Daheron, L., Brickler, T.R. et al. A comparison of non-integrating reprogramming methods Nat. Biotechnol., 33 (2015),pp. 58-63
[13]	Stadtfeld, M., Nagaya, M., Utikal, J. et al. Induced pluripotent stem cells generated without viral integration Science, 322 (2008),pp. 945-949
[14]	Su, R.J., Baylink, D.J., Neises, A. et al. Efficient generation of integration-free ips cells from human adult peripheral blood using BCL-XL together with Yamanaka factors PLoS One, 8 (2013),p. e64496
[15]	Takahashi, K., Tanabe, K., Ohnuki, M. et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell, 131 (2007),pp. 861-872
[16]	Wang, J., Gu, Q., Hao, J. et al. Generation of induced pluripotent stem cells with high efficiency from human umbilical cord blood mononuclear cells Genomics Proteomics Bioinformatics, 11 (2013),pp. 304-311
[17]	Wang, Y., Chen, J., Hu, J.L. et al. Reprogramming of mouse and human somatic cells by high-performance engineered factors EMBO Rep., 12 (2011),pp. 373-378
[18]	Warren, L., Manos, P.D., Ahfeldt, T. et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA Cell Stem Cell, 7 (2010),pp. 618-630
[19]	Yoshida, Y., Takahashi, K., Okita, K. et al. Hypoxia enhances the generation of induced pluripotent stem cells Cell Stem Cell, 5 (2009),pp. 237-241
[20]	Zhao, X.Y., Li, W., Lv, Z. et al. Efficient and rapid generation of induced pluripotent stem cells using an alternative culture medium Cell Res., 20 (2010),pp. 383-386

施引文献

资源附件(0)

访问统计

点击查看大图

计量

文章访问数: 58
HTML全文浏览量: 14
PDF下载量: 2
被引次数: 0

姓名
邮箱
手机号码
标题
留言内容
验证码

留言板

doi: 10.1016/j.jgg.2016.01.004

计量

Efficient Derivation of Human Induced Pluripotent Stem Cells with a c-Myc-Free Non-Integrating Episomal Vector

Corresponding author: E-mail address: liu086@126.com (Zhonghua Liu); E-mail address: zhouqi@ioz.ac.cn (Qi Zhou)

计量

目录

留言板

doi: 10.1016/j.jgg.2016.01.004

计量

出版历程

Efficient Derivation of Human Induced Pluripotent Stem Cells with a c-Myc-Free Non-Integrating Episomal Vector

Corresponding author: E-mail address: liu086@126.com (Zhonghua Liu); E-mail address: zhouqi@ioz.ac.cn (Qi Zhou)

计量

出版历程

目录