The Applications of Genome Editing in Xenotransplantation

a.
Avantea, Laboratory of Reproductive Technologies, Cremona, Italy
b.
Department of Veterinary Medical Sciences University of Bologna, Italy
c.
Avantea Foundation, Cremona, Italy
d.
Transplant Immunology Unit, Padua General Hospital, Padua, Italy

More Information

Corresponding author: E-mail address: cesaregalli@avantea.it (Cesare Galli)

摘要

HTML全文

参考文献(24)

[1]	Ahrens, H.E., Petersen, B., Herrmann, D. et al. siRNA mediated knockdown of tissue factor expression in pigs for xenotransplantation Am. J. Transplant., 15 (2015),pp. 1407-1414
[2]	Carroll, D. Genome engineering with targetable nucleases Annu. Rev. Biochem., 83 (2014),pp. 409-439
[3]	Conchon, S., A, P., Concordet, J.P. et al. Xenotransplantation, 20 (2013),pp. 370-371
[4]	Denner, J. Expression and function of endogenous retroviruses in the placenta A. P. M. I. S., 124 (2016),pp. 31-43
[5]	Ekser, B., Ezzelarab, M., Hara, H. et al. Clinical xenotransplantation: the next medical revolution? Lancet, 379 (2012),pp. 672-683
[6]	Estrada, J.L., Martens, G., Li, P. et al. Xenotransplantation, 22 (2015),pp. 194-202
[7]	Fishman, J.A., Scobie, L., Takeuchi, Y. Xenotransplantation-associated infectious risk: a WHO consultation Xenotransplantation, 19 (2012),pp. 72-81
[8]	Griesemer, A., Yamada, K., Sykes, M. Xenotransplantation: immunological hurdles and progress toward tolerance Immunol. Rev., 258 (2014),pp. 241-258
[9]	Hauschild, J., Petersen, B., Santiago, Y. et al. Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases Proc. Natl. Acad. Sci. USA, 108 (2011),pp. 12013-12017
[10]	Kwon, D.N., Lee, K., Kang, M.J. et al. Production of biallelic CMP-Neu5Ac hydroxylase knock-out pigs Sci. Rep., 3 (2013),p. 1981
[11]	Kobayashi, T., Yamaguchi, T., Hamanaka, S. et al. Generation of rat pancreas in mouse by interspecific blastocyst injection of pluripotent stem cells Cell, 142 (2010),pp. 787-799
[12]	Le Bas-Bernardet, S., Tillou, X., Poirier, N. et al. Xenotransplantation of galactosyl-transferase knockout, CD55, CD59, CD39, and fucosyl-transferase transgenic pig kidneys into baboons Transplant. Proc., 43 (2011),pp. 3426-3430
[13]	Lee, C.M., Cradick, T.J., Fine, E.J. et al. Nuclease target site selection for maximizing on-target activity and minimizing off-target effects in genome editing Mol. Ther., 24 (2016),pp. 475-487
[14]	Li, X., Yang, Y., Bu, L. et al. Rosa26-targeted swine models for stable gene over-expression and Cre-mediated lineage tracing Cell Res., 24 (2014),pp. 501-504
[15]	Lutz, A.J., Li, P., Estrada, J.L. et al. Double knockout pigs deficient in N-glycolylneuraminic acid and galactose alpha-1,3-galactose reduce the humoral barrier to xenotransplantation Xenotransplantation, 20 (2013),pp. 27-35
[16]	Matsunari, H., Nagashima, H., Watanabe, M. et al. Proc. Natl. Acad. Sci. USA, 110 (2013),pp. 4557-4562
[17]	Mohiuddin, M., Singh, A., Corcoran, P. et al.
[18]	Patience, C., Takeuchi, Y., Weiss, R.A. Infection of human cells by an endogenous retrovirus of pigs Nat. Med., 3 (1997),pp. 282-286
[19]	Scobie, L., Padler-Karavani, V., Le Bas-Bernardet, S. et al. Long-term IgG response to porcine Neu5Gc antigens without transmission of PERV in burn patients treated with porcine skin xenografts J. Immunol., 191 (2013),pp. 2907-2915
[20]	Usui, J., Kobayashi, T., Yamaguchi, T. et al. Am. J. Pathol., 180 (2012),pp. 2417-2426
[21]	Venables, P.J., Brookes, S.M., Griffiths, D. et al. Abundance of an endogenous retroviral envelope protein in placental trophoblasts suggests a biological function Virology, 211 (1995),pp. 589-592
[22]	Whitworth, K.M., Lee, K., Benne, J.A. et al. Biol. Reprod., 91 (2014),p. 78
[23]	Xin, J., Yang, H., Fan, N. et al. PLoS One, 8 (2013),p. e84250
[24]	Yang, L., Guell, M., Niu, D. et al. Genome-wide inactivation of porcine endogenous retroviruses (PERVs) Science, 350 (2015),pp. 1101-1104