Molecular insights of organochlorine biocide-induced toxicity in zebrafish: Whole-adult-organism toxicogenomics, targeted gene expression and histological analyses

Eei Yin Lui¹,
Caixia Li^{2, 3},
Zhi-Hua Li^{4, 5},
Zhiyuan Gong^{6, 7
, ,},
Siew Hong Lam^{6, 7
, ,}

1.
NUS Environmental Research Institute, National University of Singapore, 117411, Singapore
2.
NUS Environmental Research Institute, National University of Singapore, 117411, Singapore
3.
Department of Biological Sciences, National University of Singapore, 117543, Singapore
4.
Department of Biological Sciences, National University of Singapore, 117543, Singapore
5.
Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan 430223, China
6.
NUS Environmental Research Institute, National University of Singapore, 117411, Singapore
7.
Department of Biological Sciences, National University of Singapore, 117543, Singapore

More Information

Corresponding author: E-mail address: dbsgzy@nus.edu.sg (Zhiyuan Gong); E-mail address: dbslsh@nus.edu.sg (Siew Hong Lam)

摘要

HTML全文

参考文献(19)

[1]	Androutsopoulos, V.P., Hernandez, A.F., Liesivuori, J. et al. A mechanistic overview of health associated effects of low levels of organochlorine and organophosphorous pesticides Toxicology, 307 (2013),pp. 89-94
[2]	Bijoy Nandan, S., Nimila, P.J. Mar. Environ. Res., 76 (2012),pp. 63-70
[3]	Cohn, B.A., La Merrill, M., Krigbaum, N.Y. et al. DDT exposure in utero and breast cancer J. Clin. Endocrinol. Metab., 100 (2015),pp. 2865-2872
[4]	Cooney, M.A., Buck Louis, G.M., Hediger, M.L. et al. Organochlorine pesticides and endometriosis Reprod. Toxicol., 30 (2010),pp. 365-369
[5]	de Assis, H.C.S., Mela, M.
[6]	Feng, K., Yu, B.Y., Ge, D.M. et al. Organo-chlorine pesticide (DDT and HCH) residues in the Taihu Lake Region and its movement in soil-water system: I. Field survey of DDT and HCH residues in ecosystem of the region Chemosphere, 50 (2003),pp. 683-687
[7]	Glynn, A., Thuvander, A., Aune, M. et al. Immune cell counts and risks of respiratory infections among infants exposed pre- and postnatally to organochlorine compounds: a prospective study Environ. Health, 7 (2008),p. 62
[8]	Heusinkveld, H.J., Westerink, R.H. Organochlorine insecticides lindane and dieldrin and their binary mixture disturb calcium homeostasis in dopaminergic PC12 cells Environ. Sci. Technol., 46 (2012),pp. 1842-1848
[9]	Lam, S.H., Mathavan, S., Tong, Y. et al. Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology PLoS Genet., 4 (2008),p. e1000121
[10]	Mrema, E.J., Rubino, F.M., Brambilla, G. et al. Persistent organochlorinated pesticides and mechanisms of their toxicity Toxicology, 307 (2013),pp. 74-88
[11]	Narahashi, T. Neuronal ion channels as the target sites of insecticides Pharmacol. Toxicol., 79 (1996),pp. 1-14
[12]	Riou, V., Ndiaye, A., Budzinski, H. et al. Comp. Biochem. Physiol. C Toxicol. Pharmacol., 156 (2012),pp. 7-16
[13]	Sonne, C., Wolkers, H., Leifsson, P.S. et al. Chemosphere, 71 (2008),pp. 1214-1224
[14]	Ung, C.Y., Lam, S.H., Zhang, X. et al. Existence of inverted profile in chemically responsive molecular pathways in the zebrafish liver PLoS One, 6 (2011),p. e27819
[15]	Vijaya Padma, V., Poornima, P., Prakash, C. et al. Oral treatment with gallic acid and quercetin alleviates lindane-induced cardiotoxicity in rats Can. J. Physiol. Pharmacol., 91 (2013),pp. 134-140
[16]	Wang, D., Yu, Y., Zhang, X. et al. Organochlorine pesticides in fish from Taihu Lake, China, and associated human health risk assessment Ecotoxicol. Environ. Saf., 98 (2013),pp. 383-389
[17]	World Health Organization
[18]	Yu, W.J., Hardin, P.E. J. Cell Sci., 119 (2006),pp. 4793-4795
[19]	Zhu, H., Dahlstrom, A., Hansson, H.A. Characterization of cell proliferation in the adult dentate under normal conditions and after kainate induced seizures using ribonucleotide reductase and BrdU Brain Res., 1036 (2005),pp. 7-17

施引文献

资源附件(0)

访问统计

点击查看大图

计量

文章访问数: 71
HTML全文浏览量: 20
PDF下载量: 1
被引次数: 0

姓名
邮箱
手机号码
标题
留言内容
验证码

留言板

doi: 10.1016/j.jgg.2016.06.001

计量

Molecular insights of organochlorine biocide-induced toxicity in zebrafish: Whole-adult-organism toxicogenomics, targeted gene expression and histological analyses

Corresponding author: E-mail address: dbsgzy@nus.edu.sg (Zhiyuan Gong); E-mail address: dbslsh@nus.edu.sg (Siew Hong Lam)

计量

目录

留言板

doi: 10.1016/j.jgg.2016.06.001

计量

出版历程

Molecular insights of organochlorine biocide-induced toxicity in zebrafish: Whole-adult-organism toxicogenomics, targeted gene expression and histological analyses

Corresponding author: E-mail address: dbsgzy@nus.edu.sg (Zhiyuan Gong); E-mail address: dbslsh@nus.edu.sg (Siew Hong Lam)

计量

出版历程

目录