A 2-bp insertion (c.67_68insCC) in MC1R causes recessive white coat color in Bama miniature pigs

Qitao Jia^{1, 2, 3, #},
Chunwei Cao^{1, 2, 3, #},
Hai Tang^{1, 2, 3},
Ying Zhang^{1, 2, 3},
Qiantao Zheng^{1, 2, 3},
Xiao Wang^{1, 2, 3},
Rui Zhang^{1, 2, 3},
Xianlong Wang^{1, 2, 3},
Ailing Luo^{1, 2, 3},
Hong Wei^{4, 5},
Anming Meng^{6, 7},
Qi Zhou^{8, 9, 10},
Hongmei Wang^{8, 9, 10
, ,},
Jianguo Zhao^{8, 9, 10
, ,}

1.
State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China
2.
University of Chinese Academy of Sciences, Beijing 100049, China
3.
Chinese Swine Mutagenesis Consortium, China
4.
Department of Laboratory, College of Basic Medicine, Third Military Medical University, Chongqing 400038, China
5.
Chinese Swine Mutagenesis Consortium, China
6.
School of Life Sciences, Tsinghua University, Beijing 100084, China
7.
Chinese Swine Mutagenesis Consortium, China
8.
State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China
9.
University of Chinese Academy of Sciences, Beijing 100049, China
10.
Chinese Swine Mutagenesis Consortium, China

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Corresponding author: E-mail address: Wanghm@ioz.ac.cn (Hongmei Wang); E-mail address: zhaojg@ioz.ac.cn (Jianguo Zhao)

These authors contributed equally to this work.

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These authors contributed equally to this work.

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[1]	Andersson, L. Melanocortin receptor variants with phenotypic effects in horse, pig, and chicken Ann. N. Y. Acad. Sci., 994 (2003),pp. 313-318
[2]	Andersson, L. Studying phenotypic evolution in domestic animals: a walk in the footsteps of Charles Darwin. Cold Spring Harb Symp. Quant. Biol., 74 (2009),pp. 319-325
[3]	Barsh, G.S. The genetics of pigmentation: from fancy genes to complex traits Trends Genet., 12 (1996),pp. 299-305
[4]	Eggermont, A.M., Spatz, A., Robert, C. Cutaneous melanoma Lancet, 383 (2014),pp. 816-827
[5]	Giuffra, E., Tornsten, A., Marklund, S. et al. A large duplication associated with dominant white color in pigs originated by homologous recombination between LINE elements flanking KIT Mamm. Genome, 13 (2002),pp. 569-577
[6]	Hai, T., Teng, F., Guo, R. et al. One-step generation of knockout pigs by zygote injection of CRISPR/Cas system Cell Res., 24 (2014),pp. 372-375
[7]	Kijas, J.M., Wales, R., Tornsten, A. et al. Melanocortin receptor 1 (MC1R) mutations and coat color in pigs Genetics, 150 (1998),pp. 1177-1185
[8]	Klungland, H., Vage, D.I., Gomez-Raya, L. et al. The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination Mamm. Genome, 6 (1995),pp. 636-639
[9]	Marklund, S., Kijas, J., Rodriguez-Martinez, H. et al. Molecular basis for the dominant white phenotype in the domestic pig Genome Res., 8 (1998),pp. 826-833
[10]	Miyagi, R., Terai, Y. The diversity of male nuptial coloration leads to species diversity in Lake Victoria cichlids Genes Genet. Syst., 88 (2013),pp. 145-153
[11]	Newton, J.M., Wilkie, A.L., He, L. et al. Melanocortin 1 receptor variation in the domestic dog Mamm. Genome, 11 (2000),pp. 24-30
[12]	Robbins, L.S., Nadeau, J.H., Johnson, K.R. et al. Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function Cell, 72 (1993),pp. 827-834
[13]	Schook, L.B., Collares, T.V., Darfour-Oduro, K.A. et al. Unraveling the swine genome: implications for human health Annu. Rev. Anim. Biosci., 3 (2015),pp. 219-244
[14]	Slominski, A., Tobin, D.J., Shibahara, S. et al. Melanin pigmentation in mammalian skin and its hormonal regulation Physiol. Rev., 84 (2004),pp. 1155-1228
[15]	Sun, Z., Wang, G., Yang, X. et al. Experimental study on effect of natural hirudin on vein congestion of random skin flap in porcine models Chin. J. Reparative Reconstr. Surg., 22 (2008),pp. 1296-1300
[16]	Takeuchi, S., Suzuki, H., Yabuuchi, M. et al. A possible involvement of melanocortin 1-receptor in regulating feather color pigmentation in the chicken Biochim. Biophys. Acta, 1308 (1996),pp. 164-168
[17]	Wang, X., Cao, C., Huang, J. et al. One-step generation of triple gene-targeted pigs using CRISPR/Cas9 system Sci. Rep., 6 (2016),p. 20620
[18]	Zhang, B., Chen, B., Ma, D. et al. Establishment of a Bama miniature swine model of chronic myocardial ischemic models by thoracoscopy J. Med. Res., 43 (2014),pp. 104-107
[19]	Zhang, Y., Liu, X., Xie, L. et al. Variation of nitric oxide synthase in penis of Bama mini-pigs with diabetic erectile dysfunction Prog. Veterinary Med., 31 (2010),pp. 28-31
[20]	Zhou, X., Wang, L., Du, Y. et al. Efficient generation of gene-modified pigs harboring precise orthologous human mutation via CRISPR/Cas9-induced homology-directed repair in zygotes Hum. Mutat., 37 (2016),pp. 110-118

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期刊类型引用(10)

1.	Xu, Z., Wu, J., Zhang, Y. et al. Genome-wide detection of selection signatures in Jianli pigs reveals novel cis-regulatory haplotype in EDNRB associated with two-end black coat color. BMC Genomics, 2024, 25(1): 23. 必应学术
2.	Zheng, H., Xiong, S.-Y., Xiao, S.-J. et al. Association between MC1R gene and coat color segregation in Shanxia long black pig and Lulai black pig. BMC Genomic Data, 2023, 24(1): 74. 必应学术
3.	Giovannini, S., Strillacci, M.G., Bagnato, A. et al. Genetic and Phenotypic Characteristics of Belted Pig Breeds: A Review. Animals, 2023, 13(19): 3072. 必应学术
4.	Fontanesi, L.. Genetics and genomics of pigmentation variability in pigs: A review. Livestock Science, 2022. 必应学术
5.	Hou, N., Du, X., Wu, S. Advances in pig models of human diseases. Animal Models and Experimental Medicine, 2022, 5(2): 141-152. 必应学术
6.	Du, Z., D’alessandro, E., Zheng, Y. et al. Retrotransposon Insertion Polymorphisms (RIPs) in Pig Coat Color Candidate Genes. Animals, 2022, 12(8): 969. 必应学术
7.	Ma, Y., Zhong, Y., Guo, J. et al. CLONING AND EXPRESSION ANALYSIS OF TYR AND SLC24A5 IN ORYZIAS CELEBENSIS. Acta Hydrobiologica Sinica, 2022, 46(3): 282-291. 必应学术
8.	Nosková, A., Bhati, M., Kadri, N.K. et al. Characterization of a haplotype-reference panel for genotyping by low-pass sequencing in Swiss Large White pigs. BMC Genomics, 2021, 22(1): 290. 必应学术
9.	Zhang, W., Yang, M., Zhou, M. et al. Identification of Signatures of Selection by Whole-Genome Resequencing of a Chinese Native Pig. Frontiers in Genetics, 2020. 必应学术
10.	Shen, X., Wang, Y., Zhao, X. et al. Detection of Snps in the melanocortin 1-receptor (MC1R) and its association with shank color trait in hs chicken. Revista Brasileira de Ciencia Avicola / Brazilian Journal of Poultry Science, 2019, 21(3): eRBCA-2018-0845. 必应学术

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doi: 10.1016/j.jgg.2017.02.003

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A 2-bp insertion (c.67_68insCC) in MC1R causes recessive white coat color in Bama miniature pigs

Corresponding author: E-mail address: Wanghm@ioz.ac.cn (Hongmei Wang); E-mail address: zhaojg@ioz.ac.cn (Jianguo Zhao)

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doi: 10.1016/j.jgg.2017.02.003

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A 2-bp insertion (c.67_68insCC) in MC1R causes recessive white coat color in Bama miniature pigs

Corresponding author: E-mail address: Wanghm@ioz.ac.cn (Hongmei Wang); E-mail address: zhaojg@ioz.ac.cn (Jianguo Zhao)

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