Short body length phenotype is compensated by the upregulation of nidogen family members in a deleterious nid1a mutation of zebrafish

Peipei Zhu^{1, #},
Zhipeng Ma^{1, #},
Liwei Guo^{1, #},
Wei Zhang¹,
Qinghe Zhang¹,
Ting Zhao¹,
Kunpeng Jiang¹,
Jinrong Peng²,
Jun Chen^{3
, ,}

1.
College of Life Sciences, Zhejiang University, Hangzhou 310058, China
2.
College of Animal Sciences, Zhejiang University, Hangzhou 310058, China
3.
College of Life Sciences, Zhejiang University, Hangzhou 310058, China

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Corresponding author: E-mail address: chenJun2009@zju.edu.cn (Jun Chen)

These authors contributed equally to this work.

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These authors contributed equally to this work.

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参考文献(20)

[1]	Bader, B.L., Smyth, N., Nedbal, S. et al. Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice Mol. Cell. Biol., 25 (2005),pp. 6846-6856
[2]	Berghmans, S., Murphey, R.D., Wienholds, E. et al. Proc. Natl. Acad. Sci. U. S. A., 102 (2005),pp. 407-412
[3]	Bose, K., Nischt, R., Page, A. et al. Loss of nidogen-1 and -2 results in syndactyly and changes in limb development J. Biol. Chem., 281 (2006),pp. 39620-39629
[4]	Carlin, B., Jaffe, R., Bender, B. et al. Entactin, a novel basal lamina-associated sulfated glycoprotein J. Biol. Chem., 256 (1981),pp. 5209-5214
[5]	De Souza, A.T., Dai, X., Spencer, A.G. et al. Nucleic Acids Res., 34 (2006),pp. 4486-4494
[6]	Fleischmajer, R., Schechter, A., Bruns, M. et al. J. Invest. Dermatol., 105 (1995),pp. 597-601
[7]	Fox, J.W., Mayer, U., Nischt, R. et al. Recombinant nidogen consists of three globular domains and mediates binding of laminin to collagen type IV EMBO J., 10 (1991),pp. 3137-3146
[8]	Gao, Y.B., Zhang, Y., Zhang, D. et al. Proc. Natl. Acad. Sci. U. S. A., 112 (2015),pp. 2275-2280
[9]	Kok, F.O., Shin, M., Ni, C.W. et al. Reverse genetic screening reveals poor correlation between morpholino-induced and Mutant phenotypes in zebrafish Dev. Cell, 32 (2015),pp. 97-108
[10]	Miner, J.H., Yurchenco, P.D. Laminin functions in tissue morphogenesis Annu. Rev. Cell Dev. Biol., 20 (2004),pp. 255-284
[11]	Murshed, M., Smyth, N., Miosge, N. et al. The absence of nidogen 1 does not affect murine basement membrane formation Mol. Cell. Biol., 20 (2000),pp. 7007-7012
[12]	Nasevicius, A., Ekker, S.C. Effective targeted gene 'knockdown' in zebrafish Nat. Genet., 26 (2000),pp. 216-220
[13]	Qi, L.S., Larson, M.H., Gilbert, L.A. et al. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression Cell, 152 (2013),pp. 1173-1183
[14]	Randles, M.J., Humphries, M.J., Lennon, R. Proteomic definitions of basement membrane composition in health and disease Matrix Biol., 57–58 (2017),pp. 12-28
[15]	Robu, M.E., Larson, J.D., Nasevicius, A. et al. p53 activation by knockdown technologies PLoS Genet., 3 (2007),p. e78
[16]	Rossi, A., Kontarakis, Z., Gerri, C. et al. Genetic compensation induced by deleterious mutations but not gene knockdowns Nature, 524 (2015),pp. 230-233
[17]	Schymeinsky, J., Nedbal, S., Miosge, N. et al. Mol. Cell. Biol., 22 (2002),pp. 6820-6830
[18]	Timpl, R., Brown, J.C. Supramolecular assembly of basement membranes Bioessays, 18 (1996),pp. 123-132
[19]	Timpl, R., Dziadek, M., Fujiwara, S. et al. Nidogen: a new, self-aggregating basement membrane protein Eur. J. Biochem., 137 (1983),pp. 455-465
[20]	Wei, S., Dai, M., Liu, Z. et al. The guanine nucleotide exchange factor Net1 facilitates the specification of dorsal cell fates in zebrafish embryos by promoting maternal beta-catenin activation Cell Res., 27 (2017),pp. 202-225