Gut microbiota from end-stage renal disease patients disrupt gut barrier function by excessive production of phenol

Xifan Wang^{1, 2},
Yanling Hao³,
Xiaoxue Liu^{4, 5},
Shoujuan Yu^{6, 7},
Weibo Zhang⁸,
Songtao Yang⁹,
Zhengquan Yu^{10
, ,},
Fazheng Ren^{11, 12
, ,}

1.
Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing, 100083, China
2.
Key Laboratory of Functional Dairy, Ministry of Education, Beijing, 100083, China
3.
Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing, 100083, China
4.
Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing, 100083, China
5.
Key Laboratory of Functional Dairy, Ministry of Education, Beijing, 100083, China
6.
Key Laboratory of Functional Dairy, Ministry of Education, Beijing, 100083, China
7.
Beijing Laboratory of Food Quality and Safety, Beijing, 100083, China
8.
Beijing Laboratory of Food Quality and Safety, Beijing, 100083, China
9.
Department of Nephrology, Aerospace Central Hospital (Aerospace Clinical Medical College of Peking University), Beijing, 100049, China
10.
Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing, 100083, China
11.
Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing, 100083, China
12.
Key Laboratory of Functional Dairy, Ministry of Education, Beijing, 100083, China

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Corresponding author: E-mail address: zyu@cau.edu.cn (Zhengquan Yu); E-mail address: renfazheng@cau.edu.cn (Fazheng Ren)

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[7]	Goncalves, S., Pecoits, R., Perreto, S., Barberato, S.H., Stinghen, A.E.M., Lima, E.G.A., Fuerbringer, R., Sauthier, S.M., Riella, M.C., 2006. Associations between renal function, volume status and endotoxaemia in chronic kidney disease patients. Nephrol. Dial. Transpl. 21, 2788-2794.
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[15]	McDonald, T.A., Holland, N.T., Skibola, C., Duramad, P., Smith, M.T., 2001. Hypothesis: Phenol and hydroquinone derived mainly from diet and gastrointestinal flora activity are causal factors in leukemia. Leukemia 15, 10-20.
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doi: 10.1016/j.jgg.2019.03.015

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Gut microbiota from end-stage renal disease patients disrupt gut barrier function by excessive production of phenol

Corresponding author: E-mail address: zyu@cau.edu.cn (Zhengquan Yu); E-mail address: renfazheng@cau.edu.cn (Fazheng Ren)

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doi: 10.1016/j.jgg.2019.03.015

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Gut microbiota from end-stage renal disease patients disrupt gut barrier function by excessive production of phenol

Corresponding author: E-mail address: zyu@cau.edu.cn (Zhengquan Yu); E-mail address: renfazheng@cau.edu.cn (Fazheng Ren)

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