Disruptor of telomeric silencing 1-like (DOT1L) is involved in breast cancer metastasis via transcriptional regulation of MALAT1 and ZEB2

Yang Duan^{1, 2},
Xingyan Zhang³,
Lihong Yang⁴,
Xu Dong⁵,
Zhanye Zheng⁶,
Yiming Cheng⁷,
Hao Chen⁸,
Bei Lan⁹,
Dengwen Li¹⁰,
Jun Zhou^{11, 12},
Chenghao Xuan^{13
, ,}

1.
Tianjin Key Laboratory of Medical Epigenetics, Key Laboratory of Breast Cancer Prevention and Therapy (Ministry of Education), Tianjin Key Laboratory of Spine and Spinal Cord, Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin, 300070, China
2.
Department of Gynecology, Tianjin Medical University NanKai Hospital, Tianjin 300100, China
3.
Tianjin Key Laboratory of Medical Epigenetics, Key Laboratory of Breast Cancer Prevention and Therapy (Ministry of Education), Tianjin Key Laboratory of Spine and Spinal Cord, Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin, 300070, China
4.
Department of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin 300071, China
5.
Tianjin Key Laboratory of Medical Epigenetics, Key Laboratory of Breast Cancer Prevention and Therapy (Ministry of Education), Tianjin Key Laboratory of Spine and Spinal Cord, Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin, 300070, China
6.
Department of Pharmacology, Tianjin Medical University, Tianjin, 300070, China
7.
Tianjin Key Laboratory of Medical Epigenetics, Key Laboratory of Breast Cancer Prevention and Therapy (Ministry of Education), Tianjin Key Laboratory of Spine and Spinal Cord, Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin, 300070, China
8.
Tianjin Key Laboratory of Medical Epigenetics, Key Laboratory of Breast Cancer Prevention and Therapy (Ministry of Education), Tianjin Key Laboratory of Spine and Spinal Cord, Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin, 300070, China
9.
Tianjin Key Laboratory of Medical Epigenetics, Key Laboratory of Breast Cancer Prevention and Therapy (Ministry of Education), Tianjin Key Laboratory of Spine and Spinal Cord, Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin, 300070, China
10.
Department of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin 300071, China
11.
Department of Genetics and Cell Biology, College of Life Sciences, Nankai University, Tianjin 300071, China
12.
Institute of Biomedical Sciences, College of Life Sciences, Shandong Normal University, Shandong 250014, China
13.
Tianjin Key Laboratory of Medical Epigenetics, Key Laboratory of Breast Cancer Prevention and Therapy (Ministry of Education), Tianjin Key Laboratory of Spine and Spinal Cord, Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin, 300070, China

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Corresponding author: E-mail address: chenghaoxuan@tmu.edu.cn (Chenghao Xuan)

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参考文献(20)

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