Variants in the Wnt co-receptor <i>LRP6</i> are associated with familial exudative vitreoretinopathy

Shujin Li; Mu Yang; Yunqi He; Xiaoyan Jiang; Rulian Zhao; Wenjing Liu; Lulin Huang; Yi Shi; Xiao Li; Kuanxiang Sun; Yeming Yang; Periasamy Sundaresan; Peiquan Zhao; Zhenglin Yang; Xianjun Zhu

doi:10.1016/j.jgg.2021.11.010

文章导航 > Journal of Genetics and Genomics > 2022 > 49(6): 590-594

Shujin Li, Mu Yang, Yunqi He, Xiaoyan Jiang, Rulian Zhao, Wenjing Liu, Lulin Huang, Yi Shi, Xiao Li, Kuanxiang Sun, Yeming Yang, Periasamy Sundaresan, Peiquan Zhao, Zhenglin Yang, Xianjun Zhu. Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy[J]. 遗传学报, 2022, 49(6): 590-594. doi: 10.1016/j.jgg.2021.11.010

引用本文:

Shujin Li, Mu Yang, Yunqi He, Xiaoyan Jiang, Rulian Zhao, Wenjing Liu, Lulin Huang, Yi Shi, Xiao Li, Kuanxiang Sun, Yeming Yang, Periasamy Sundaresan, Peiquan Zhao, Zhenglin Yang, Xianjun Zhu. Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy[J]. 遗传学报, 2022, 49(6): 590-594. doi: 10.1016/j.jgg.2021.11.010

Shujin Li, Mu Yang, Yunqi He, Xiaoyan Jiang, Rulian Zhao, Wenjing Liu, Lulin Huang, Yi Shi, Xiao Li, Kuanxiang Sun, Yeming Yang, Periasamy Sundaresan, Peiquan Zhao, Zhenglin Yang, Xianjun Zhu. Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy[J]. Journal of Genetics and Genomics, 2022, 49(6): 590-594. doi: 10.1016/j.jgg.2021.11.010

Citation:

Shujin Li, Mu Yang, Yunqi He, Xiaoyan Jiang, Rulian Zhao, Wenjing Liu, Lulin Huang, Yi Shi, Xiao Li, Kuanxiang Sun, Yeming Yang, Periasamy Sundaresan, Peiquan Zhao, Zhenglin Yang, Xianjun Zhu. Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy[J]. Journal of Genetics and Genomics, 2022, 49(6): 590-594. doi: 10.1016/j.jgg.2021.11.010

引用本文:

Shujin Li, Mu Yang, Yunqi He, Xiaoyan Jiang, Rulian Zhao, Wenjing Liu, Lulin Huang, Yi Shi, Xiao Li, Kuanxiang Sun, Yeming Yang, Periasamy Sundaresan, Peiquan Zhao, Zhenglin Yang, Xianjun Zhu. Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy[J]. 遗传学报, 2022, 49(6): 590-594. doi: 10.1016/j.jgg.2021.11.010

Shujin Li, Mu Yang, Yunqi He, Xiaoyan Jiang, Rulian Zhao, Wenjing Liu, Lulin Huang, Yi Shi, Xiao Li, Kuanxiang Sun, Yeming Yang, Periasamy Sundaresan, Peiquan Zhao, Zhenglin Yang, Xianjun Zhu. Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy[J]. Journal of Genetics and Genomics, 2022, 49(6): 590-594. doi: 10.1016/j.jgg.2021.11.010

Citation:

Shujin Li, Mu Yang, Yunqi He, Xiaoyan Jiang, Rulian Zhao, Wenjing Liu, Lulin Huang, Yi Shi, Xiao Li, Kuanxiang Sun, Yeming Yang, Periasamy Sundaresan, Peiquan Zhao, Zhenglin Yang, Xianjun Zhu. Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy[J]. Journal of Genetics and Genomics, 2022, 49(6): 590-594. doi: 10.1016/j.jgg.2021.11.010

Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy

doi: 10.1016/j.jgg.2021.11.010

Shujin Li^1,2,3,
Mu Yang^1,2,3,
Yunqi He^1,2,3,
Xiaoyan Jiang⁴,
Rulian Zhao⁴,
Wenjing Liu⁴,
Lulin Huang^5,6,7,
Yi Shi^5,6,7,
Xiao Li⁸,
Kuanxiang Sun⁸,
Yeming Yang⁸,
Periasamy Sundaresan⁹,
Peiquan Zhao¹⁰,
Zhenglin Yang^11,12,13, ,,
Xianjun Zhu^{14,15,16,17, ,}

1. Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China;
2. Natural Products Research Center, Institute of Chengdu Biology, Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, Sichuan 610072, China;
3. Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, Sichuan 610072, China;
4. Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China;
5. Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China;
6. Natural Products Research Center, Institute of Chengdu Biology, Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, Sichuan 610072, China;
7. Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, Sichuan 610072, China;
8. Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China;
9. Department of Genetics, Aravind Medical Research Foundation, Aravind Eye Hospital, Madurai, India;
10. Department of Ophthalmology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China;
11. Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China;
12. Natural Products Research Center, Institute of Chengdu Biology, Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, Sichuan 610072, China;
13. Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, Sichuan 610072, China;
14. Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China;
15. Natural Products Research Center, Institute of Chengdu Biology, Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, Sichuan 610072, China;
16. Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, Sichuan 610072, China;
17. Henan Eye Institute, Henan Eye Hospital, People’s Hospital of Zhengzhou University, Henan Provincial People’s Hospital, Zhengzhou, Henan 450003, China

基金项目:

This study was supported by the National Natural Science Foundation of China (81970841 and 81770950 to X. Zhu, 81790643 and 82121003 to Z. Yang, 82000913 to S. Li, 82101153 to M. Yang), the CAMS Innovation Fund for Medical Sciences (2019–12M-5-032 to Z. Yang), the Department of Science and Technology of Sichuan Province (2021YFS0386 to X. Zhu, 2022YFS0598 to S. Li, 2021YFS0369 and 2021JDGD0036 to Z. Yang), The Program of Science and Technology International Cooperation Project of Qinghai province (2022-HZ-814 to X. Zhu) and the fund for Sichuan Provincial People’s Hospital (2021QN01 to M. Yang), the Department of Chengdu Science and Technology (2021-YF05-01316-SN to X. Zhu). The funders had no role in the study design, data collection and analysis, or preparation of the manuscript.

详细信息

通讯作者:
Zhenglin Yang,E-mail:zliny@yahoo.com

Xianjun Zhu,E-mail:xjzhu@uestc.edu.cn

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出版历程
- 收稿日期: 2021-08-30
- 录用日期: 2021-11-30
- 修回日期: 2021-11-30
- 刊出日期: 2022-06-30

Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy

Shujin Li^1,2,3,
Mu Yang^1,2,3,
Yunqi He^1,2,3,
Xiaoyan Jiang⁴,
Rulian Zhao⁴,
Wenjing Liu⁴,
Lulin Huang^5,6,7,
Yi Shi^5,6,7,
Xiao Li⁸,
Kuanxiang Sun⁸,
Yeming Yang⁸,
Periasamy Sundaresan⁹,
Peiquan Zhao¹⁰,
Zhenglin Yang^{11,12,13
, ,},
Xianjun Zhu^{14,15,16,17
, ,}

1. Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China;
2. Natural Products Research Center, Institute of Chengdu Biology, Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, Sichuan 610072, China;
3. Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, Sichuan 610072, China;
4. Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China;
5. Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China;
6. Natural Products Research Center, Institute of Chengdu Biology, Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, Sichuan 610072, China;
7. Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, Sichuan 610072, China;
8. Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China;
9. Department of Genetics, Aravind Medical Research Foundation, Aravind Eye Hospital, Madurai, India;
10. Department of Ophthalmology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China;
11. Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China;
12. Natural Products Research Center, Institute of Chengdu Biology, Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, Sichuan 610072, China;
13. Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, Sichuan 610072, China;
14. Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China;
15. Natural Products Research Center, Institute of Chengdu Biology, Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, Sichuan 610072, China;
16. Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, Sichuan 610072, China;
17. Henan Eye Institute, Henan Eye Hospital, People’s Hospital of Zhengzhou University, Henan Provincial People’s Hospital, Zhengzhou, Henan 450003, China

Funds:

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参考文献(19)

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Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy

doi: 10.1016/j.jgg.2021.11.010

通讯作者:
Zhenglin Yang,E-mail:zliny@yahoo.com

Xianjun Zhu,E-mail:xjzhu@uestc.edu.cn

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Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy

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留言板

Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy

doi: 10.1016/j.jgg.2021.11.010

通讯作者: Zhenglin Yang,E-mail:zliny@yahoo.com Xianjun Zhu,E-mail:xjzhu@uestc.edu.cn

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出版历程

Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy

计量

出版历程

目录

通讯作者:
Zhenglin Yang,E-mail:zliny@yahoo.com

Xianjun Zhu,E-mail:xjzhu@uestc.edu.cn