Efficient silencing of the multicopy <i>DUX4</i> gene by ABE-mediated start codon mutation in human embryos

Yubing Liu; Xinmei Lu; Min Ye; Ling Wang; Rongxin Tang; Zhiyong Yang; Bongkoch Turathum; Chenchen Liu; Yujing Xue; Menghua Wu; Yannan Yang; Ermeng Gao; Di Zhang; Feng Yang; Keh-Kooi Kee; Xingxu Huang; Guanglei Li; Ri-Cheng Chian

doi:10.1016/j.jgg.2022.02.010

文章导航 > Journal of Genetics and Genomics > 2022 > 49(10): 982-985

Yubing Liu, Xinmei Lu, Min Ye, Ling Wang, Rongxin Tang, Zhiyong Yang, Bongkoch Turathum, Chenchen Liu, Yujing Xue, Menghua Wu, Yannan Yang, Ermeng Gao, Di Zhang, Feng Yang, Keh-Kooi Kee, Xingxu Huang, Guanglei Li, Ri-Cheng Chian. Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos[J]. 遗传学报, 2022, 49(10): 982-985. doi: 10.1016/j.jgg.2022.02.010

引用本文:

Yubing Liu, Xinmei Lu, Min Ye, Ling Wang, Rongxin Tang, Zhiyong Yang, Bongkoch Turathum, Chenchen Liu, Yujing Xue, Menghua Wu, Yannan Yang, Ermeng Gao, Di Zhang, Feng Yang, Keh-Kooi Kee, Xingxu Huang, Guanglei Li, Ri-Cheng Chian. Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos[J]. 遗传学报, 2022, 49(10): 982-985. doi: 10.1016/j.jgg.2022.02.010

Yubing Liu, Xinmei Lu, Min Ye, Ling Wang, Rongxin Tang, Zhiyong Yang, Bongkoch Turathum, Chenchen Liu, Yujing Xue, Menghua Wu, Yannan Yang, Ermeng Gao, Di Zhang, Feng Yang, Keh-Kooi Kee, Xingxu Huang, Guanglei Li, Ri-Cheng Chian. Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos[J]. Journal of Genetics and Genomics, 2022, 49(10): 982-985. doi: 10.1016/j.jgg.2022.02.010

Citation:

Yubing Liu, Xinmei Lu, Min Ye, Ling Wang, Rongxin Tang, Zhiyong Yang, Bongkoch Turathum, Chenchen Liu, Yujing Xue, Menghua Wu, Yannan Yang, Ermeng Gao, Di Zhang, Feng Yang, Keh-Kooi Kee, Xingxu Huang, Guanglei Li, Ri-Cheng Chian. Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos[J]. Journal of Genetics and Genomics, 2022, 49(10): 982-985. doi: 10.1016/j.jgg.2022.02.010

引用本文:

Yubing Liu, Xinmei Lu, Min Ye, Ling Wang, Rongxin Tang, Zhiyong Yang, Bongkoch Turathum, Chenchen Liu, Yujing Xue, Menghua Wu, Yannan Yang, Ermeng Gao, Di Zhang, Feng Yang, Keh-Kooi Kee, Xingxu Huang, Guanglei Li, Ri-Cheng Chian. Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos[J]. 遗传学报, 2022, 49(10): 982-985. doi: 10.1016/j.jgg.2022.02.010

Yubing Liu, Xinmei Lu, Min Ye, Ling Wang, Rongxin Tang, Zhiyong Yang, Bongkoch Turathum, Chenchen Liu, Yujing Xue, Menghua Wu, Yannan Yang, Ermeng Gao, Di Zhang, Feng Yang, Keh-Kooi Kee, Xingxu Huang, Guanglei Li, Ri-Cheng Chian. Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos[J]. Journal of Genetics and Genomics, 2022, 49(10): 982-985. doi: 10.1016/j.jgg.2022.02.010

Citation:

Yubing Liu, Xinmei Lu, Min Ye, Ling Wang, Rongxin Tang, Zhiyong Yang, Bongkoch Turathum, Chenchen Liu, Yujing Xue, Menghua Wu, Yannan Yang, Ermeng Gao, Di Zhang, Feng Yang, Keh-Kooi Kee, Xingxu Huang, Guanglei Li, Ri-Cheng Chian. Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos[J]. Journal of Genetics and Genomics, 2022, 49(10): 982-985. doi: 10.1016/j.jgg.2022.02.010

Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos

doi: 10.1016/j.jgg.2022.02.010

1. Center for Reproductive Medicine, Tenth People's Hospital of Tongji University, 301 Middle Yanchang Road, Shanghai 200072, China;
2. Center for Reproductive Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai 200032, China;
3. Center for Stem Cell Biology and Regenerative Medicine, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China;
4. Center for Reproductive Medicine, Tenth People's Hospital of Tongji University, 301 Middle Yanchang Road, Shanghai 200072, China;
5. Department of Basic Medical Science, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok 10300, Thailand;
6. Center for Reproductive Medicine, Tenth People's Hospital of Tongji University, 301 Middle Yanchang Road, Shanghai 200072, China;
7. Center for Stem Cell Biology and Regenerative Medicine, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China;
8. School of Life Science and Technology, Shanghai Tech University, 100 Haike Road, Pudong New Area, Shanghai 201210, China;
9. Center for Reproductive Medicine, Tenth People's Hospital of Tongji University, 301 Middle Yanchang Road, Shanghai 200072, China

基金项目:

D Program of China (2017YFC1002003), and the project sponsored by the National Natural Science Foundation of China (31601197).

This work was supported by the National Key R&

详细信息

通讯作者:
Guanglei Li,E-mail:ligl@shanghaitech.edu.cn

Ri-Cheng Chian,E-mail:rcchian@tongji.edu.cn

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出版历程
- 收稿日期: 2021-09-08
- 录用日期: 2022-02-17
- 修回日期: 2022-01-26
- 刊出日期: 2022-02-26

Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos

1. Center for Reproductive Medicine, Tenth People's Hospital of Tongji University, 301 Middle Yanchang Road, Shanghai 200072, China;
2. Center for Reproductive Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai 200032, China;
3. Center for Stem Cell Biology and Regenerative Medicine, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China;
4. Center for Reproductive Medicine, Tenth People's Hospital of Tongji University, 301 Middle Yanchang Road, Shanghai 200072, China;
5. Department of Basic Medical Science, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok 10300, Thailand;
6. Center for Reproductive Medicine, Tenth People's Hospital of Tongji University, 301 Middle Yanchang Road, Shanghai 200072, China;
7. Center for Stem Cell Biology and Regenerative Medicine, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China;
8. School of Life Science and Technology, Shanghai Tech University, 100 Haike Road, Pudong New Area, Shanghai 201210, China;
9. Center for Reproductive Medicine, Tenth People's Hospital of Tongji University, 301 Middle Yanchang Road, Shanghai 200072, China

Funds:

D Program of China (2017YFC1002003), and the project sponsored by the National Natural Science Foundation of China (31601197).

This work was supported by the National Key R&

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参考文献(27)

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Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos

doi: 10.1016/j.jgg.2022.02.010

通讯作者:
Guanglei Li,E-mail:ligl@shanghaitech.edu.cn

Ri-Cheng Chian,E-mail:rcchian@tongji.edu.cn

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Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos

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Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos

doi: 10.1016/j.jgg.2022.02.010

通讯作者: Guanglei Li,E-mail:ligl@shanghaitech.edu.cn Ri-Cheng Chian,E-mail:rcchian@tongji.edu.cn

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出版历程

Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos

计量

出版历程

目录

通讯作者:
Guanglei Li,E-mail:ligl@shanghaitech.edu.cn

Ri-Cheng Chian,E-mail:rcchian@tongji.edu.cn