Differential regulation of JAK1 expression by ETS1 associated with predisposition to primary biliary cholangitis

• Peng Jiang¹ , 
• Chan Wang² , 
• Mingming Zhang¹ , 
• Ye Tian³ , 
• Weifeng Zhao⁴ , 
• Junyi Xin⁵ , 
• Yexi Huang¹ , 
• Zhibin Zhao⁶ , 
• Wenjuan Sun¹ , 
• Jie Long⁶ , 
• Ruqi Tang⁷ , 
• Fang Qiu⁸ , 
• Xingjuan Shi¹ , 
• Yi Zhao⁹ , 
• Li Zhu¹⁰ , 
• Na Dai¹¹ , 
• Lei Liu¹² , 
• Xudong Wu¹³ , 
• Jinshan Nie¹⁴ , 
• Bo Jiang¹⁵ , 
• Youlin Shao¹⁶ , 
• Yueqiu Gao¹⁷ , 
• Jianjiang Yu¹⁸ , 
• Zhigang Hu¹⁹ , 
• Zhidong Zang²⁰ , 
• Yuhua Gong²¹ , 
• Yaping Dai²² , 
• Lan Wang²³ , 
• Ningling Ding¹⁰ , 
• Ping Xu¹⁰ , 
• Sufang Chen¹⁰ , 
• Lu Wang¹ , 
• Jing Xu²⁴ , 
• Luyao Zhang¹ , 
• Junyan Hong¹ , 
• Ruonan Qian¹ , 
• Hu Li¹ , 
• Xuan Jiang¹ , 
• Congwei Chen¹ , 
• Wenyan Tian⁴ , 
• Jian Wu⁴ , 
• Yuzhang Jiang²⁵ , 
• Chongxu Han²⁶ , 
• Kui Zhang²⁷ , 
• Hong Qiu²³ , 
• Li Li²⁴ , 
• Hong Fan²⁸ , 
• Liming Chen²⁹ , 
• Jianqiong Zhang^1,28 , 
• Zhongsheng Sun³⁰ , 
• Xiao Han³¹ , 
• Zhenhua Dai³² , 
• Erguang Li³³ , 
• M. Eric Gershwin³⁴ , 
• Zhexiong Lian⁶ , 
• Xiong Ma⁷ , 
• Michael F. Seldin³⁵ , 
• Weichang Chen^{4 , ,}  , 
• Meilin Wang^{5 , ,}  , 
• Xiangdong Liu^{1 , ,} 

• 1. Key Laboratory of Developmental Genes and Human Diseases, School of Life Science and Technology, Southeast University, Nanjing, Jiangsu 210096, China;

• 2. Institute of Translational Medicine, Yangzhou University Medical College, Yangzhou, Jiangsu 225009, China;

• 3. Department of Radiology & Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215004, China;

• 4. The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, China;

• 5. Department of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, Center for Global Health, Nanjing Medical University School of Public Health, Nanjing, Jiangsu 210029, China;

• 6. Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, China;

• 7. Department of Gastroenterology and Hepatology, Shanghai Institute of Digestive Diseases, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital, Shanghai 200001, China;

• 8. Department of Laboratory Medicine, The Fourth Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210031, China;

• 9. Department of Gastrointestinal Endoscopy, Eastern Hepatobiliary Surgery Hospital, Shanghai 201800, China;

• 10. The Fifth People's Hospital, Soochow University, Suzhou, Jiangsu 215007, China;

• 11. Department of Gastroenterology, Jiangsu University Affiliated Kunshan Hospital, Kunshan, Jiangsu 215300, China;

• 12. Department of Gastroenterology, Yixing People's Hospital, Yixin, Jiangsu 214200, China;

• 13. Department of Gastroenterology, Yancheng First People's Hospital, Yancheng, Jiangsu 224005, China;

• 14. Department of Gastroenterology, Taicang First People's Hospital, Soochow University, Taicang, Jiangsu 215400, China;

• 15. Department of Hepatology, Jingjiang Second People's Hospital, Jingjiang, Jiangsu 214500, China;

• 16. Department of Hepatology, The Third People's Hospital of Changzhou, Changzhou, Jiangsu 213001, China;

• 17. Department of Liver Diseases, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;

• 18. Department of Laboratory Medicine, Jiangyin People's Hospital, Southeast University, Jiangyin, Jiangsu 214400, China;

• 19. Department of Laboratory Medicine, Wuxi Children's Hospital, Wuxi, Jiangsu 214023, China;

• 20. Department of Hepatology, The Second Hospital of Nanjing, Southeast University, Nanjing, Jiangsu 210003, China;

• 21. Department of Laboratory Medicine, The Third People's Hospital of Zhenjiang, Zhenjiang, Jiangsu 212021, China;

• 22. Department of Laboratory Medicine, The Fifth People's Hospital of Wuxi, Wuxi, Jiangsu 214000, China;

• 23. Department of Laboratory Medicine, The 81th Hospital of PLA, Nanjing, Jiangsu 210002, China;

• 24. Department of Clinical Laboratory, Southeast University ZhongDa Hospital, Nanjing, Jiangsu 210009, China;

• 25. Department of Laboratory Medicine, Huai'an First People's Hospital, Nanjing Medical University, Huai'an, Jiangsu 223300, China;

• 26. Department of Laboratory Medicine, Subei People's Hospital, Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu 225001, China;

• 27. Department of Laboratory Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu 210008, China;

• 28. Southeast University Medical College, Nanjing, Jiangsu 210009, China;

• 29. Jiangsu Key Laboratory for Molecular and Medical Biotechnology, Institute of cancer, Department of biochemistry, Nanjing Normal University College of Life Sciences, Nanjing, Jiangsu 210023, China;

• 30. Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China;

• 31. Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing, Jiangsu 211166, China;

• 32. Section of Immunology & Joint Immunology Program, the Second Clinical Medical College of Guangzhou University of Chinese Medicine, and Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, Guangdong 510006, China;

• 33. Jiangsu Laboratory of Molecular Medicine, Nanjing University Medical School, Nanjing, Jiangsu 210093, China;

• 34. Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis School of Medicine, Davis, CA, 95616, USA;

• 35. Department of Biochemistry and Molecular Medicine, University of California at Davis School of Medicine, Davis, CA, 95616, USA