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Natural variation in the SVP contributes to the pleiotropic adaption of Arabidopsis thaliana across contrasted habitats

Xiang Guo,  Ruyun Liang,  Shangling Lou,  Jing Hou,  Liyang Chen,  Xin Liang,  Xiaoqin Feng,  Yingjun Yao,  Jianquan Liu,  Huanhuan Liu

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文章导航 > Journal of Genetics and Genomics  > 2023 > 优先出版
Xiang Guo, Ruyun Liang, Shangling Lou, Jing Hou, Liyang Chen, Xin Liang, Xiaoqin Feng, Yingjun Yao, Jianquan Liu, Huanhuan Liu. Natural variation in the SVP contributes to the pleiotropic adaption of Arabidopsis thaliana across contrasted habitats[J]. 遗传学报. doi: 10.1016/j.jgg.2023.08.004
引用本文: Xiang Guo, Ruyun Liang, Shangling Lou, Jing Hou, Liyang Chen, Xin Liang, Xiaoqin Feng, Yingjun Yao, Jianquan Liu, Huanhuan Liu. Natural variation in the SVP contributes to the pleiotropic adaption of Arabidopsis thaliana across contrasted habitats[J]. 遗传学报. doi: 10.1016/j.jgg.2023.08.004
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Xiang Guo, Ruyun Liang, Shangling Lou, Jing Hou, Liyang Chen, Xin Liang, Xiaoqin Feng, Yingjun Yao, Jianquan Liu, Huanhuan Liu. Natural variation in the SVP contributes to the pleiotropic adaption of Arabidopsis thaliana across contrasted habitats[J]. Journal of Genetics and Genomics. doi: 10.1016/j.jgg.2023.08.004
Citation: Xiang Guo, Ruyun Liang, Shangling Lou, Jing Hou, Liyang Chen, Xin Liang, Xiaoqin Feng, Yingjun Yao, Jianquan Liu, Huanhuan Liu. Natural variation in the SVP contributes to the pleiotropic adaption of Arabidopsis thaliana across contrasted habitats[J]. Journal of Genetics and Genomics. doi: 10.1016/j.jgg.2023.08.004
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Natural variation in the SVP contributes to the pleiotropic adaption of Arabidopsis thaliana across contrasted habitats

doi: 10.1016/j.jgg.2023.08.004

  • Key Laboratory for Bio-Resource and Eco-Environment of Ministry of Education & Sichuan Zoige Alpine Wetland Ecosystem National Observation and Research Station, College of Life Science, Sichuan University, Chengdu, Sichuan, 610065, China

基金项目: 

This work was supported by the Natural Science Foundation of China (No. 32030006 and No. 32270302), the Strategic Priority Research Program of the Chinese Academy of Sciences (No. XDB31000000), and the Fundamental Research Funds for the Central Universities (2020SCUNL207 and SCU2022D003).

详细信息
    通讯作者:

    Jianquan Liu,Email addresses:liujq@nwipb.cas.cn

    Huanhuan Liu,Email addresses:liuhuanhuan85@163.com

Natural variation in the SVP contributes to the pleiotropic adaption of Arabidopsis thaliana across contrasted habitats

  • Key Laboratory for Bio-Resource and Eco-Environment of Ministry of Education & Sichuan Zoige Alpine Wetland Ecosystem National Observation and Research Station, College of Life Science, Sichuan University, Chengdu, Sichuan, 610065, China

Funds: 

This work was supported by the Natural Science Foundation of China (No. 32030006 and No. 32270302), the Strategic Priority Research Program of the Chinese Academy of Sciences (No. XDB31000000), and the Fundamental Research Funds for the Central Universities (2020SCUNL207 and SCU2022D003).

    摘要
  • 摘要:

    Coordinated plant adaptation involves the interplay of multiple traits driven by habitat- specific selection pressures. Pleiotropic effects, wherein genetic variants of a single gene control multiple traits, can expedite such adaptations. Until present, only a limited number of genes have been reported to exhibit pleiotropy. Here, we create a recombinant inbred line (RIL) population derived from two Arabidopsis thaliana (A. thaliana) ecotypes originating from divergent habitats. Using this RIL population, we identify an allelic variation in a MADS-box transcription factor, SHORT VEGETATIVE PHASE (SVP), which exerts a pleiotropic effect on leaf size and drought-versus-humidity tolerance. Further investigation reveals that a natural null variant of the SVP protein disrupts its normal regulatory interactions with target genes, including GRF3, CYP707A1/3, and AtBG1, leading to increased leaf size, enhanced tolerance to humid conditions, and changed in flowering time in humid conditions in A. thaliana. Remarkably, polymorphic variations in this gene have been traced back to early A. thaliana populations, providing a genetic foundation and plasticity for subsequent colonization of diverse habitats by influencing multiple traits. These findings advance our understanding of how plants rapidly adapt to changing environments by virtue of the pleiotropic effects of individual genes on multiple trait alterations.

    Abstract:

    Coordinated plant adaptation involves the interplay of multiple traits driven by habitat- specific selection pressures. Pleiotropic effects, wherein genetic variants of a single gene control multiple traits, can expedite such adaptations. Until present, only a limited number of genes have been reported to exhibit pleiotropy. Here, we create a recombinant inbred line (RIL) population derived from two Arabidopsis thaliana (A. thaliana) ecotypes originating from divergent habitats. Using this RIL population, we identify an allelic variation in a MADS-box transcription factor, SHORT VEGETATIVE PHASE (SVP), which exerts a pleiotropic effect on leaf size and drought-versus-humidity tolerance. Further investigation reveals that a natural null variant of the SVP protein disrupts its normal regulatory interactions with target genes, including GRF3, CYP707A1/3, and AtBG1, leading to increased leaf size, enhanced tolerance to humid conditions, and changed in flowering time in humid conditions in A. thaliana. Remarkably, polymorphic variations in this gene have been traced back to early A. thaliana populations, providing a genetic foundation and plasticity for subsequent colonization of diverse habitats by influencing multiple traits. These findings advance our understanding of how plants rapidly adapt to changing environments by virtue of the pleiotropic effects of individual genes on multiple trait alterations.

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