9.9
CiteScore
7.1
Impact Factor

2008 Vol. 35, No. 10

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Research article
Developmental systems biology flourishing on new technologies
Jing-Dong J. Han, Yi Liu, Huiling Xue, Kai Xia, Hong Yu, Shanshan Zhu, Zhang Chen, Wei Zhang, Zheng Huang, Chunyu Jin, Bo Xian, Jing Li, Lei Hou, Yixing Han, Chaoqun Niu, Timothy C. Alcon
2008, 35(10): 577-584. doi: 10.1016/S1673-8527(08)60078-8
Abstract (89) HTML PDF (1)
Abstract:
Organism development is a systems level process. It has benefited greatly from the recent technological advances in the field of systems biology. DNA microarray, phenome, interactome and transcriptome mapping, the new generation of deep sequencing technologies, and faster and better computational an...
The genomic landscapes of histone H3-Lys9 modifications of gene promoter regions and expression profiles in human bone marrow mesenchymal stem cells
Jiang Tan, Hui Huang, Wei Huang, Lin Li, Jianhua Guo, Baiqu Huang, Jun Lu
2008, 35(10): 585-593. doi: 10.1016/S1673-8527(08)60079-X
Abstract (101) HTML PDF (0)
Abstract:
Mesenchymal stem cells (MSCs) of nonembryonic origins possess the proliferation and multi-lineage differentiation potentials. It has been established that epigenetic mechanisms could be critical for determining the fate of stem cells, and MSCs derived from different origins exhibited different expre...
Amelioration of β654-thalassemia in mouse model with the knockdown of aberrantly spliced β-globin mRNA
Shuyang Xie, Wei Li, Zhaorui Ren, Jingzhi Zhang, Xinbin Guo, Shu Wang, Shuzhen Huang, Fanyi Zeng, Yi-Tao Zeng
2008, 35(10): 595-601. doi: 10.1016/S1673-8527(08)60080-6
Abstract (113) HTML PDF (1)
Abstract:
Large amounts of aberrantly spliced mRNA from the β654 allele was present in erythroid cells, which might impair the erythropoiesis. A therapeutic strategy for β-thalassemia was explored by knocking down the aberrantly spliced mRNA of β-globin. Lentiviral vector with siRNA fragment targets on the sp...
Floret-specific differences in gene expression and support for the hypothesis that tapetal degeneration of Zea mays L. occurs via programmed cell death
David S. Skibbe, Xiujuan Wang, Lisa A. Borsuk, Daniel A. Ashlock, Dan Nettleton, Patrick S. Schnable
2008, 35(10): 603-616. doi: 10.1016/S1673-8527(08)60081-8
Abstract (114) HTML PDF (1)
Abstract:
The maize (Zea mays) spikelet consists of two florets, each of which contains three developmentally synchronized anthers. Morphologically, the anthers in the upper and lower florets proceed through apparently similar developmental programs. To test for global differences in gene expression and to id...
Production of aneuhaploid and euhaploid sporocytes by meiotic restitution in fertile hybrids between durum wheat Langdon chromosome substitution lines and Aegilops tauschii
Lianquan Zhang, Qijiao Chen, Zhongwei Yuan, Zhiguo Xiang, Youliang Zheng, Dengcai Liu
2008, 35(10): 617-623. doi: 10.1016/S1673-8527(08)60082-X
Abstract (135) HTML PDF (1)
Abstract:
Fertile F1 hybrids were obtained between durum wheat (Triticum durum Desf.) Langdon (LDN) and its 10 disomic substitution (LDN DS) lines with Aegilops tauschii accession AS60 without embryo rescue. Selfed seedset rates for hybrids of LDN with AS60 were 36.87% and 49.45% in 2005 and 2006, respectivel...
Validation of EST-derived STS markers localized on Qfhs.ndsu-3BS for Fusarium head blight resistance in wheat using a ‘Wangshuibai’ derived population
Amir Mohammad Naji, Mohammad Moghaddam, Mohammad Reza Ghaffari, Hashem Pour Irandoost, Laleh Karimi Farsad, Seyed Mostafa Pirseyedi, Seyed Abolghasem Mohammadi, Behzad Ghareyazie, Mohsen Mardi
2008, 35(10): 625-629. doi: 10.1016/S1673-8527(08)60083-1
Abstract (85) HTML PDF (0)
Abstract:
A few EST-derived STS markers localized on Qfhs.ndsu-3BS, a major QTL for resistance to Fusarium head blight (FHB) in wheat, have been previously identified in the ‘Sumai 3’/‘Stoa’ population. In this study, we used a ‘Wangshuibai’ (resistant) /‘Seri82’ (susceptible) derived population, linkage grou...
Isolation and characterization of two genes encoding polygalacturonase-inhibiting protein from Populus deltoides
Qiang Cheng, Youzhi Cao, Huixin Pan, Mingxiu Wang, Minren Huang
2008, 35(10): 631-638. doi: 10.1016/S1673-8527(08)60084-3
Abstract (86) HTML PDF (1)
Abstract:
Polygalacturonase-inhibiting proteins (PGIPs) are extracellular proteins that belong to the leucine-rich repeat (LRR) protein superfamily. PGIPs inhibit fungal polygalacturonases (PGs) and promote accumulation of oligogalacturonides, which activate plant defense responses. PGIPs play important roles...