5.9
CiteScore
5.9
Impact Factor

2019 Vol. 46, No. 10

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Review
Acquisition of functional neurons by direct conversion: Switching the developmental clock directly
Shuangquan Chen, Juan Zhang, Dongming Zhang, Jianwei Jiao
2019, 46(10): 459-465. doi: 10.1016/j.jgg.2019.10.003
Abstract (111) HTML PDF (2)
Abstract:
Identifying approaches for treating neurodegeneration is a thorny task but is important for a growing number of patients. Researchers have focused on discovering the underlying molecular mechanisms of reprogramming and optimizing the technologies for acquiring neurons. Direct conversion is one of th...
Histone modifications and their regulatory roles in plant development and environmental memory
Ting Zhao, Zhenping Zhan, Danhua Jiang
2019, 46(10): 467-476. doi: 10.1016/j.jgg.2019.09.005
Abstract (186) HTML PDF (14)
Abstract:
Plants grow in dynamic environments where they receive diverse environmental signals. Swift and precise control of gene expression is essential for plants to align their development and metabolism with fluctuating surroundings. Modifications on histones serve as “histone code” to specify chromatin a...
Original research
RASSF6-TRIM16 axis promotes cell proliferation, migration and invasion in esophageal squamous cell carcinoma
Leilei Zheng, Zitong Zhao, Lulu Rong, Liyan Xue, Yongmei Song
2019, 46(10): 477-488. doi: 10.1016/j.jgg.2019.10.004
Abstract (104) HTML PDF (3)
Abstract:
Ras-association (RA) domain family number 6 (RASSF6) is a member of the Ras-association domain protein family. It is epigenetically inactive and negatively regulates the malignant progression of some tumors. However, its precise role in esophageal squamous cell carcinoma (ESCC) has not been reported...
Embryonic lineage tracing with Procr-CreER marks balanced hematopoietic stem cell fate during entire mouse lifespan
Xiaona Zheng, Guangyu Zhang, Yandong Gong, Xiaowei Ning, Zhijie Bai, Jian He, Fan Zhou, Yanli Ni, Yu Lan, Bing Liu
2019, 46(10): 489-498. doi: 10.1016/j.jgg.2019.10.005
Abstract (139) HTML PDF (2)
Abstract:
The functional heterogeneity of hematopoietic stem cells (HSCs) has been comprehensively investigated by single-cell transplantation assay. However, the heterogeneity regarding their physiological contribution remains an open question, especially for those with life-long hematopoietic fate of rigoro...
Letter to the editor
Evolutionary selection on MDA5 and LGP2 in the chicken preserves antiviral competence in the absence of RIG-I
Ling Xu, Dandan Yu, Yu Fan, Yi-Ping Liu, Yong-Gang Yao
2019, 46(10): 499-503. doi: 10.1016/j.jgg.2019.10.001
Abstract (116) HTML PDF (2)
Abstract:
Rapid breeding of pink-fruited tomato hybrids using the CRISPR/Cas9 system
Tianxia Yang, Lei Deng, Wei Zhao, Ruoxi Zhang, Hongling Jiang, Zhibiao Ye, Chang-Bao Li, Chuanyou Li
2019, 46(10): 505-508. doi: 10.1016/j.jgg.2019.10.002
Abstract (205) HTML PDF (18)
Abstract: