An everlasting role of animal models in understanding human disease

Yang Xiao; Yang Chonglin

doi:10.1016/S1673-8527(09)60075-8

Volume 37 Issue 9

Sep. 2010

Turn off MathJax

Article Contents

References

Article Navigation > Journal of Genetics and Genomics > 2010 > 37(9): 557

PDF( 143 KB)

An everlasting role of animal models in understanding human disease

doi: 10.1016/S1673-8527(09)60075-8

Yang Xiao^a,
Yang Chonglin^b

a
Genetic Laboratory of Development and Diseases, State Key Laboratory of Proteomics, Institute of Biotechnology, Beijing 100071, China
b
Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100190, China

Available Online: 2010-10-07
Publish Date: 2010-09-20

Abstract

FullText(HTML)

References(0)

References

Relative Articles

[1]	Huanju Liu, Mixue Tu, Zhiyong Yin, Dan Zhang, Jun Ma, Feng He. Unraveling the complexity of polycystic ovary syndrome with animal models[J]. Journal of Genetics and Genomics. doi: 10.1016/j.jgg.2023.09.012
[2]	Brecht Driesschaert, Lucas Mergan, Liesbet Temmerman. Conditional gene expression in invertebrate animal models[J]. Journal of Genetics and Genomics, 2021, 48(1): 14-31. doi: 10.1016/j.jgg.2021.01.005
[3]	Raoxu Wang, Bowen Li, Sin Man Lam, Guanghou Shui. Integration of lipidomics and metabolomics for in-depth understanding of cellular mechanism and disease progression[J]. Journal of Genetics and Genomics, 2020, 47(2): 69-83. doi: 10.1016/j.jgg.2019.11.009
[4]	Zhe Chen, Fan Zhang, Hong Xu. Human mitochondrial DNA diseases and Drosophila models[J]. Journal of Genetics and Genomics, 2019, 46(4): 201-212. doi: 10.1016/j.jgg.2019.03.009
[5]	Arindam Bhattacharjee, Áron Szabó, Tamás Csizmadia, Hajnalka Laczkó-Dobos, Gábor Juhász. Understanding the importance of autophagy in human diseases using Drosophila[J]. Journal of Genetics and Genomics, 2019, 46(4): 157-169. doi: 10.1016/j.jgg.2019.03.007
[6]	Jun-Yuan Ji, Chun Han, Wu-Min Deng. Understanding human diseases using Drosophila[J]. Journal of Genetics and Genomics, 2019, 46(4): 155-156. doi: 10.1016/j.jgg.2019.04.001
[7]	Weiwei Ma, Mengnan Wu, Siyan Zhou, Ye Tao, Zuolei Xie, Yi Zhong. Reduced Smoothened level rescues Aβ-induced memory deficits and neuronal inflammation in animal models of Alzheimer's disease[J]. Journal of Genetics and Genomics, 2018, 45(5): 237-246. doi: 10.1016/j.jgg.2018.05.001
[8]	Shuang Yang, Guoqing Zhang, Wan Liu, Zhen Wang, Jifeng Zhang, Dongshan Yang, Y. Eugene Chen, Hong Sun, Yixue Li. SysFinder: A customized platform for search, comparison and assisted design of appropriate animal models based on systematic similarity[J]. Journal of Genetics and Genomics, 2017, 44(5): 251-258. doi: 10.1016/j.jgg.2017.05.001
[9]	Olfat Al-Harazi, Sadiq Al Insaif, Monirah A. Al-Ajlan, Namik Kaya, Nduna Dzimiri, Dilek Colak. Integrated Genomic and Network-Based Analyses of Complex Diseases and Human Disease Network[J]. Journal of Genetics and Genomics, 2016, 43(6): 349-367. doi: 10.1016/j.jgg.2015.11.002
[10]	JoAnne J. Babula, Jing-Yuan Liu. Integrate Omics Data and Molecular Dynamics Simulations toward Better Understanding of Human 14-3-3 Interactomes and Better Drugs for Cancer Therapy[J]. Journal of Genetics and Genomics, 2015, 42(10): 531-547. doi: 10.1016/j.jgg.2015.09.002
[11]	Yong-Gang Yao, Yong-Bin Chen, Bin Liang. The 3rd Symposium on Animal Models of Primates – The Application of Non-Human Primates to Basic Research and Translational Medicine[J]. Journal of Genetics and Genomics, 2015, 42(6): 339-341. doi: 10.1016/j.jgg.2015.04.007
[12]	Nana Fan, Liangxue Lai. Genetically Modified Pig Models for Human Diseases[J]. Journal of Genetics and Genomics, 2013, 40(2): 67-73. doi: 10.1016/j.jgg.2012.07.014
[13]	Yongchang Chen, Yuyu Niu, Weizhi Ji. Transgenic Nonhuman Primate Models for Human Diseases: Approaches and Contributing Factors[J]. Journal of Genetics and Genomics, 2012, 39(6): 247-251. doi: 10.1016/j.jgg.2012.04.007
[14]	Richard L. Carter, Anthony W.S. Chan. Pluripotent Stem Cells Models for Huntington's Disease: Prospects and Challenges[J]. Journal of Genetics and Genomics, 2012, 39(6): 253-259. doi: 10.1016/j.jgg.2012.04.006
[15]	Xiao-Jiang Li, Shihua Li. Influence of Species Differences on the Neuropathology of Transgenic Huntington's Disease Animal Models[J]. Journal of Genetics and Genomics, 2012, 39(6): 239-245. doi: 10.1016/j.jgg.2012.05.002
[16]	Tatsuo Kido, Stephanie Schubert, Jörg Schmidtke, Yun-Fai Chris Lau. Expression of the human TSPY gene in the brains of transgenic mice suggests a potential role of this Y chromosome gene in neural functions[J]. Journal of Genetics and Genomics, 2011, 38(5): 181-191. doi: 10.1016/j.jgg.2011.04.002
[17]	Mao Liu, Huiping Chen. The role of microRNAs in colorectal cancer[J]. Journal of Genetics and Genomics, 2010, 37(6): 347-358. doi: 10.1016/S1673-8527(09)60053-9
[18]	Yoichi Gondo. Now and future of mouse mutagenesis for human disease models[J]. Journal of Genetics and Genomics, 2010, 37(9): 559-572. doi: 10.1016/S1673-8527(09)60076-X
[19]	Wai-Yee Chan, Stephen T.S. Lam, Bai-Lin Wu. An everlasting role of genetics and genomics in public health: a meeting report of ACGA-HKSMG International Conference on Genetic and Genomic Medicine 2008[J]. Journal of Genetics and Genomics, 2009, 36(4): 189-190. doi: 10.1016/S1673-8527(08)60105-8
[20]	Lee M Butcher, Stephan Beck. Future impact of integrated high-throughput methylome analyses on human health and disease[J]. Journal of Genetics and Genomics, 2008, 35(7): 391-401. doi: 10.1016/S1673-8527(08)60057-0