Rare variants in <italic>FANCJ</italic> induce premature ovarian insufficiency in humans and mice

Xi Yang; Shuting Ren; Jialin Yang; Yuncheng Pan; Zixue Zhou; Qing Chen; Yunzheng Fang; Lingyue Shang; Feng Zhang; Xiaojin Zhang; Yanhua Wu

doi:10.1016/j.jgg.2023.03.013

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Rare variants in FANCJ induce premature ovarian insufficiency in humans and mice

doi: 10.1016/j.jgg.2023.03.013

1
State Key Laboratory of Genetic Engineering at School of Life Sciences, Human Phenome Institute, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200438, China
2
Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, Shanghai 200011, China
3
Human Phenome Institute, Zhangjiang Fudan International Innovation Center, Fudan University, Shanghai 201203, China
4
Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai 200011, China
5
State Key Laboratory of Genetic Engineering at School of Life Sciences, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200438, China
6
National Demonstration Center for Experimental Biology Education, School of Life Sciences, Fudan University, Shanghai 200433, China

Funds: The authors gratefully thank the patients for participating and supporting this study. This work was supported by National Natural Science Foundation of China (32270658 and 32288101), National Key Research and Development Program of China (2022YFC2703800) and Natural Science Foundation of Shanghai (20ZR1407000).

Received Date: 2022-12-08
Revised Date: 2023-03-20
Accepted Date: 2023-03-29

Available Online: 2023-04-14

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References(19)

References

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