ABE-induced <i>PDGFD</i> start codon silencing unveils new insights into the genetic architecture of sheep fat tails

Peter Kalds; Shuhong Huang; Siyuan Xi; Yumeng Fang; Yawei Gao; Shiwei Zhou; Kexin Sun; Chao Li; Bei Cai; Yao Liu; Yige Ding; Qifang Kou; Tad Sonstegard; Bj&#246;rn Petersen; Stephen Kemp; Baohua Ma; Jian-Lin Han; Yulin Chen; Xiaolong Wang

doi:10.1016/j.jgg.2023.07.008

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ABE-induced PDGFD start codon silencing unveils new insights into the genetic architecture of sheep fat tails

doi: 10.1016/j.jgg.2023.07.008

1 International Joint Agriculture Research Center for Animal Bio-breeding, Ministry of Agriculture and Rural Affairs/Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China;
2 Department of Animal and Poultry Production, Faculty of Environmental Agricultural Sciences, Arish University, El-Arish 45511, Egypt;
3 College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China;
4 Key Laboratory of Ruminant Molecular and Cellular Breeding, School of Agriculture, Ningxia;
University, Yinchuan 750000, China;
5 Ningxia Tianyuan Tan Sheep Farm, Hongsibu 751999, China;
6 Acceligen Inc., St. Paul, MN 55104, United States;
7 Institute of Farm Animal Genetics, Friedrich-Loeffler-Institut, Mariensee, Neustadt am Rübenberge 31535, Germany;
8 International Livestock Research Institute (ILRI), Nairobi 30709-00100, Kenya;
9 CAAS-ILRI Joint Laboratory on Livestock and Forage Genetic Resources, Institute of Animal Science, Chinese Academy of Agricultural Sciences (CAAS), Beijing 100193, China;
10 Key Laboratory of Livestock Biology, Northwest A&F University, Yangling 712100, China

Funds:

This work was supported by the National Natural Science Foundation of China (32161143010, 32072719, and 31972526), the China Postdoctoral Science Foundation (2021M700111), the China Agriculture Research System (CARS-39-03), and local grants (2022GD-TSLD-46, NXTS2021-001, and 2020KW-028).

Received Date: 2023-01-28
Accepted Date: 2023-07-28
Rev Recd Date: 2023-07-13

Available Online: 2023-07-31

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