Human genetic disorders result from genetic abnormalities or complex interactions between genes and environmental factors. The study of human genetic diseases is crucial for understanding the intricate relationship between our genes and our health. In recent years, significant progress has been made in areas such as the identification of disease-causing genes, unraveling molecular mechanisms, improving animal models, developing bioinformatics tools and databases, and advancing gene therapy technologies in the field of human genetic diseases. This special issue on Human Genetic Disorders explores research advancements in the molecular mechanisms of genetic diseases, the development of new bioinformatics tools and databases, gene therapy techniques for genetic disorders, animal models of human genetic diseases, and the study of non-coding variants associated with genetic diseases.

Edited by Huijun Yuan, Zhenglin Yang, Zhi-Ying Wu, Wei Li

Volume 51, Issue 2,

Pages 111-264 (February 2024)